Electron microscopy study of human myeloma immunoglobulin G1

Scanning electron microscopy of myeloma cells.

The surface structure of myeloma cells was examined by scanning electron microscopy. The cells were collected from the pleural effusion of a multiple myeloma patient and purified by Conray-Ficoll gradient sedimentation. The cell size ranged from 8 mu to 12 mu in diameter and the microvilli were from 0.8 mu to 1.2 mu in length. The surfaces of the majority of the observed myeloma cells were more...

Electron Microscopy of Polyribosomes Synthesizing Immunoglobulin Chains

Polyribosomes from the immunoglobulin-producing plasma-cell tumour X5563 were fractionated on a linear sucrose gradient and fractions containing polyribosomes carrying heavy (H) and light (L) immunoglobulin chains were examined with the electron microscope. The size distribution of the polyribosomes in the various fractions was determined. The results are consistent with previous estimates by W...

Electron Microscopy of Fowl Pox Virus

Examination of Lung Parenchyma by Electron Microscopy

In this paper many of the principal struc­ture of the Moral Lung were studied with the help of Electron Microscopy. Detailed descrip­tion was given of Granular Pneumocytes, Membranous Pneumocytes, Macrophages, and Alveolar Capillaries. A discussion followed on the form and function of Granular Pneumo­cytes.  Acknowledgements  I am grateful to the Reza Shah Pahlavi Foundation for its generou...

Electron Microscope Study of Surface Immunoglobulin-bearing Human Tonsil Cells

Surface immunoglobulin-bearing cells were selected from suspensions of human tonsil cells by the reverse immune cytoadherence technique. The method employed a hybrid antibody directed against Ig on lymphoid cells and against ferritin bound to sheep red blood cells (SRBC). Only 6% of the cells formed rosettes. When subjected to electron microscopy they were shown to consist of a morphologically ...